Drug-drug interactions between vitamin K antagonists and statins: a systematic review | Zendy

Anna Elise Engell | Zendy; Andreas Ludvig Ohm Svendsen | Zendy; Bent Lind | Zendy; Tore Bjerregaard Stage | Zendy; Maja Hellfritzsch | Zendy; Anton Pottegård | Zendy

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Drug-drug interactions between vitamin K antagonists and statins: a systematic review

Author(s) -

Anna Elise Engell,

Andreas Ludvig Ohm Svendsen,

Bent Lind,

Tore Bjerregaard Stage,

Maja Hellfritzsch,

Anton Pottegård

Publication year - 2021

Publication title -

european journal of clinical pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.845

H-Index - 108

eISSN - 1432-1041

pISSN - 0031-6970

DOI - 10.1007/s00228-020-03074-w

Subject(s) - medicine , warfarin , simvastatin , vitamin k antagonist , statin , concomitant , drug , vitamin k , anticoagulant , drug interaction , pharmacology , atrial fibrillation

Concomitant use of vitamin K antagonists (VKA) and statins is frequent in cardiovascular patients. However, clinical guidelines on this drug combination are divergent. Therefore, we performed a systematic review to evaluate the effect of statin initiation on coagulation among VKA users.

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