Proton pump inhibitors and risk of liver cancer and mortality in patients with chronic liver disease: a systematic review and meta-analysis | Zendy

Hyun Jin Song | Zendy; Xinyi Jiang | Zendy; Linda Henry | Zendy; Mindie H. Nguyen | Zendy; Haesuk Park | Zendy

Open Access

Proton pump inhibitors and risk of liver cancer and mortality in patients with chronic liver disease: a systematic review and meta-analysis

Author(s) -

Hyun Jin Song,

Xinyi Jiang,

Linda Henry,

Mindie H. Nguyen,

Haesuk Park

Publication year - 2020

Publication title -

european journal of clinical pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.845

H-Index - 108

eISSN - 1432-1041

pISSN - 0031-6970

DOI - 10.1007/s00228-020-02854-8

Subject(s) - medicine , relative risk , meta analysis , liver cancer , cochrane library , cancer , confidence interval , chronic liver disease , hepatocellular carcinoma , observational study , liver disease , epidemiology , gastroenterology , cirrhosis

Epidemiological studies investigating the use of proton pump inhibitors (PPI) on the risk of liver cancer and/or mortality among persons with chronic liver disease (CLD) have reported conflicting results. We conducted a systematic review and meta-analysis to determine the impact of PPI use on liver cancer and/or death among patients with CLD.

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