Biosensors as new analytical tool for detection of Genetically Modified Organisms (GMOs) | Zendy

Maria Minunni | Zendy; Sara Tombelli | Zendy; Elisa Mariotti | Zendy; Marco Mascini | Zendy; Marcello Mascini | Zendy

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Biosensors as new analytical tool for detection of Genetically Modified Organisms (GMOs)

Author(s) -

Maria Minunni,

Sara Tombelli,

Elisa Mariotti,

Marco Mascini,

Marcello Mascini

Publication year - 2001

Publication title -

fresenius journal of analytical chemistry

Language(s) - English

Resource type - Journals

eISSN - 1432-1130

pISSN - 0937-0633

DOI - 10.1007/s002160100761

Subject(s) - biosensor , analyte , nucleic acid , genetically engineered , nanotechnology , genetically modified organism , transduction (biophysics) , aptamer , chemistry , combinatorial chemistry , materials science , biology , biochemistry , chromatography , microbiology and biotechnology , gene

Three different biosensors for detection of Genetically Modified Organisms (GMOs) are presented. The sensing principle is based on the affinity interaction between nucleic acids: the probe is immobilised on the sensor surface and the target analyte is free in solution. The immobilised probes are specific for most inserted sequences in GMOs: the promoter P35S and the terminator TNOS. Electrochemical methods with screen-printed electrodes, piezoelectric and optical (SPR) transduction principles were applied.

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