Open AccessThreshold dose for intravenous nicotine self-administration in young adult non-dependent smokers
Author(s) -
R. Ross MacLean,
Elise E. DeVito,
Tore Eid,
Suprit Parida,
Ralitza Gueorguieva,
Mehmet Sofuoglu
Publication year - 2021
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-021-05833-8
Subject(s) - nicotine , placebo , self administration , abstinence , saline , medicine , alkaloid , anesthesia , nicotine addiction , dose–response relationship , addiction , reinforcement , pharmacology , psychology , psychiatry , chemistry , social psychology , stereochemistry , alternative medicine , pathology
Reducing nicotine content of inhaled tobacco products may prevent nicotine addiction, but the threshold for nicotine reinforcement has not been systematically evaluated in controlled human laboratory studies.