Open AccessInhaled corticosteroids as treatment for adolescent asthma: effects on adult anxiety-related outcomes in a murine model
Author(s) -
Jasmine I. Caulfield,
Allison M. Ching,
Erin M. Cover,
Avery August,
Timothy J. Craig,
Helen M. Kamens,
Sonia A. Cavigelli
Publication year - 2020
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-020-05666-x
Subject(s) - anxiety , medicine , asthma , corticosterone , corticosteroid , glucocorticoid , generalized anxiety disorder , immunology , endocrinology , psychiatry , hormone
Allergic asthma, typically controlled with inhaled corticosteroids (ICS), is the leading chronic health condition for youth under 18 years of age. During this peri-adolescent period, significant brain maturation occurs. Prior studies indicate that both chronic inflammation and corticosteroid medications increase risk for developing an internalizing disorder like anxiety.