Open AccessActive vaccination reduces reinforcing effects of MDPV in male Sprague-Dawley rats trained to self-administer cocaine
Author(s) -
Samantha J. McClenahan,
Melinda G. Gunnell,
S. Michael Owens,
William E. Fantegrossi
Publication year - 2020
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-020-05558-0
Subject(s) - self administration , medicine , pharmacology , vaccination , immunology
3,4-Methylenedioxypyrovalerone (MDPV) is a synthetic cathinone abused for its cocaine-like psychostimulant effects in "bath salts" products. While there are currently no pharmacotherapies for MDPV abuse, rodent studies suggest immunotherapy may offer a feasible treatment option.