Open AccessPoor inhibitory control is associated with greater stimulation and less sedation following alcohol
Author(s) -
Jessica Weafer,
K. Luan Phan,
Harriet de Wit
Publication year - 2019
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-019-05420-y
Subject(s) - stimulant , sedative , alcohol , alcohol use disorder , sedation , inhibitory control , placebo , psychology , stimulation , inhibitory postsynaptic potential , ethanol , medicine , anesthesia , psychiatry , cognition , chemistry , biochemistry , alternative medicine , organic chemistry , pathology
Poor inhibitory control is a well-established risk factor for alcohol use disorder (AUD). Similarly, greater sensitivity to the stimulant effects and less sensitivity to the sedative effects of alcohol are also strongly linked to risk for AUD. Traditionally, these two risk factors have been considered to be orthogonal, and thus they have been studied independently. However, recent evidence from animal and human studies suggests that they may be related. The current study examined the relationship between inhibitory control and subjective responses to alcohol in a sample of healthy young adults.