
Nicotine e-cigarette vapor inhalation effects on nicotine & cotinine plasma levels and somatic withdrawal signs in adult male Wistar rats
Author(s) -
Christian Montanari,
Leslie K. Kelley,
Tony M. Kerr,
Maury Cole,
Nicholas W. Gilpin
Publication year - 2019
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-019-05400-2
Subject(s) - nicotine , cotinine , inhalation , nicotine withdrawal , mecamylamine , anesthesia , chemistry , physiology , pharmacology , medicine , nicotinic agonist , receptor
Non-contingent chronic nicotine exposure procedures have evolved rapidly in recent years, culminating in electronic nicotine delivery systems (ENDS or e-cigarettes) to deliver vaporized drugs to rodents in standard housing chambers.