Open AccessSelf-administered nicotine increases fat metabolism and suppresses weight gain in male rats
Author(s) -
Laura E. Rupprecht,
Alison D. Kreisler,
Samantha R. Spierling,
Giordano de Guglielmo,
Marsida Kallupi,
Olivier George,
Eric C. Donny,
Eric P. Zorrilla,
Alan F. Sved
Publication year - 2018
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-018-4830-y
Subject(s) - nicotine , endocrinology , medicine , meal , respiratory exchange ratio , resting energy expenditure , weight gain , thermogenesis , energy expenditure , body weight , obesity , heart rate , blood pressure
The ability of nicotine to suppress body weight is cited as a factor impacting smoking initiation and the failure to quit. Self-administered nicotine in male rats suppresses weight independent of food intake, suggesting that nicotine increases energy expenditure.