Reduction in delay discounting due to nicotine and its attenuation by cholinergic antagonists in Lewis and Fischer 344 rats | Zendy

Jenny E. Ozga | Zendy; Karen G. Anderson | Zendy

Open Access

Reduction in delay discounting due to nicotine and its attenuation by cholinergic antagonists in Lewis and Fischer 344 rats

Author(s) -

Jenny E. Ozga,

Karen G. Anderson

Publication year - 2017

Publication title -

psychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.378

H-Index - 196

eISSN - 1432-2072

pISSN - 0033-3158

DOI - 10.1007/s00213-017-4752-0

Subject(s) - cholinergic , nicotine , attenuation , delay discounting , reduction (mathematics) , discounting , cholinergic system , endocrinology , pharmacology , medicine , psychology , mathematics , economics , physics , geometry , finance , optics

Nicotine acts as an agonist for nicotinic acetylcholine receptors (nAChRs), and mecamylamine, a nonselective nAChR antagonist, attenuates effects of nicotine on delay discounting in some rat strains; whether nicotine's attenuation is specific to nAChR antagonism is unknown.

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