Open AccessAdolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice
Author(s) -
Yurie Matsumoto,
Minae Niwa,
Akihiro Mouri,
Yukihiro Noda,
Takeshi Fukushima,
Norio Ozaki,
Toshitaka Nabeshima
Publication year - 2017
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-017-4704-8
Subject(s) - glutamatergic , dopaminergic , prefrontal cortex , neuroscience , glutamate receptor , schizophrenia (object oriented programming) , nmda receptor , psychology , dopamine , disc1 , biology , medicine , receptor , psychiatry , genetics , cognition , gene
Stress during the adolescent period influences postnatal maturation and behavioral patterns in adulthood. Adolescent stress-induced molecular and functional changes in neurons are the key clinical features of psychiatric disorders including schizophrenia.