Effects of clozapine on behavioral and metabolic traits relevant for schizophrenia in two mouse strains
Author(s) -
Jean Mary Zarate,
Patricia Boksa,
Trino Baptista,
Ridha Joober
Publication year - 2004
Publication title -
psychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-003-1553-4
Subject(s) - prepulse inhibition , clozapine , amphetamine , schizophrenia (object oriented programming) , antipsychotic , psychosis , psychology , strain (injury) , pharmacology , medicine , endocrinology , neuroscience , psychiatry , dopamine
Schizophrenia is a heterogeneous syndrome both at the etiological and clinical levels. In particular, patients with schizophrenia exhibit important variability in their therapeutic and metabolic responses to clozapine, an antipsychotic medication.
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