Open AccessGuidelines for the assessment of bone density and microarchitecture in vivo using high-resolution peripheral quantitative computed tomography
Author(s) -
Danielle E. Whittier,
Steven K. Boyd,
Andrew J. Burghardt,
Julien Paccou,
Ali GhasemZadeh,
Roland Chapurlat,
Klaus Engelke,
Mary L. Bouxsein
Publication year - 2020
Publication title -
osteoporosis international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 170
eISSN - 1433-2965
pISSN - 0937-941X
DOI - 10.1007/s00198-020-05438-5
Subject(s) - quantitative computed tomography , medicine , medical physics , terminology , standardization , radiology , nuclear medicine , osteoporosis , computer science , bone density , pathology , linguistics , philosophy , operating system
The application of high-resolution peripheral quantitative computed tomography (HR-pQCT) to assess bone microarchitecture has grown rapidly since its introduction in 2005. As the use of HR-pQCT for clinical research continues to grow, there is an urgent need to form a consensus on imaging and analysis methodologies so that studies can be appropriately compared. In addition, with the recent introduction of the second-generation HrpQCT, which differs from the first-generation HR-pQCT in scan region, resolution, and morphological measurement techniques, there is a need for guidelines on appropriate reporting of results and considerations as the field adopts newer systems.