Open AccessAssociation between a literature-based genetic risk score and bone mineral density of African American women in Women Health Initiative Study
Author(s) -
Xiangxue Xiao,
Qing Wu
Publication year - 2019
Publication title -
osteoporosis international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 170
eISSN - 1433-2965
pISSN - 0937-941X
DOI - 10.1007/s00198-019-05244-8
Subject(s) - medicine , femoral neck , single nucleotide polymorphism , bone mineral , imputation (statistics) , osteoporosis , genome wide association study , demography , cohort , genetic association , oncology , genotype , genetics , biology , gene , machine learning , sociology , missing data , computer science
Genetic risk of low BMD in African American women remains unclear. Based on SNPs discovered from a predominantly Caucasian sample, genetic profile was summarized and was found to be significantly associated with BMD variation in African American women.