Open AccessChange in HbA1c over 3 years does not improve the prediction of cardiovascular disease over and above HbA1c measured at a single time point
Author(s) -
Parinya Chamnan,
Rebecca K. Simmons,
KayTee Khaw,
Nicholas J. Wareham,
Simon J. Griffin
Publication year - 2013
Publication title -
diabetologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.464
H-Index - 227
eISSN - 1432-0428
pISSN - 0012-186X
DOI - 10.1007/s00125-013-2854-8
Subject(s) - medicine , european prospective investigation into cancer and nutrition , disease , proportional hazards model , incidence (geometry) , population , framingham risk score , prospective cohort study , risk factor , receiver operating characteristic , diabetes mellitus , demography , environmental health , endocrinology , physics , sociology , optics
HbA1c is an important risk factor for cardiovascular disease (CVD), with 1% higher HbA1c levels associated with a 10-20% increased risk of CVD. Little is known about the association between change in HbA1c over time and cardiovascular risk in non-diabetic populations. This study examined the association between change in HbA1c over time and cardiovascular risk in a non-diabetic British population.