Open AccessGestörtes Gleichgewicht von Immunsystem und Hautmikrobiom bei chronisch entzündlichen Dermatosen
Author(s) -
Marcus Kuchner,
Jaemmer,
Thomas Werfel,
Bernhard Homey
Publication year - 2021
Publication title -
der hautarzt
Language(s) - German
Resource type - Journals
SCImago Journal Rank - 0.221
H-Index - 39
eISSN - 1432-1173
pISSN - 0017-8470
DOI - 10.1007/s00105-021-04832-2
Subject(s) - atopic dermatitis , medicine , psoriasis , microbiome , dermatology , immunology , clinical significance , immune system , pathology , bioinformatics , biology
The skin is an organ frequently affected by chronic diseases. Inflammatory, immune-mediated dermatoses such as atopic dermatitis and psoriasis show a high prevalence as well as a significant impact on the quality of life of those affected. In a large proportion of cases, atopic dermatitis is associated with a marked change in microbial colonization of both clinically healthy and affected skin. In psoriasis, changes to this effect have been described, but clinical relevance remains elusive.