Open AccessRegional Metabolite Concentrations in Aging Human Brain: Comparison of Short-TE Whole Brain MR Spectroscopic Imaging and Single Voxel Spectroscopy at 3T
Author(s) -
Helen Maghsudi,
Birte Schmitz,
Andrew A. Maudsley,
Sulaiman Sheriff,
Paul Bronzlik,
Martin Schütze,
Heinrich Lanfermann,
XiaoQi Ding
Publication year - 2019
Publication title -
clinical neuroradiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.792
H-Index - 27
eISSN - 1869-1447
pISSN - 1869-1439
DOI - 10.1007/s00062-018-00757-x
Subject(s) - metabolite , in vivo magnetic resonance spectroscopy , voxel , white matter , in vivo , creatine , nuclear medicine , human brain , chemistry , choline , magnetic resonance imaging , medicine , biology , neuroscience , biochemistry , radiology , microbiology and biotechnology
The aim of this study was to compare a recently established whole brain MR spectroscopic imaging (wbMRSI) technique using spin-echo planar spectroscopic imaging (EPSI) acquisition and the Metabolic Imaging and Data Analysis System (MIDAS) software package with single voxel spectroscopy (SVS) technique and LCModel analysis for determination of relative metabolite concentrations in aging human brain.