Open AccessVamorolone, a dissociative steroidal compound, reduces collagen antibody-induced joint damage and inflammation when administered after disease onset
Author(s) -
Jesse M. Damsker,
Michaelyn R. Cornish,
Priya Kanneboyina,
Ila Kanneboyina,
Qing Yu,
Rachel Lipson,
Aditi Phadke,
Susan M. Knoblach,
Karuna Panchapakesan,
Melissa Morales,
Alyson A. Fiorillo,
Terence A. Partridge,
Kanneboyigaraju
Publication year - 2019
Publication title -
inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.121
H-Index - 89
eISSN - 1420-908X
pISSN - 1023-3830
DOI - 10.1007/s00011-019-01279-z
Subject(s) - medicine , prednisolone , rheumatoid arthritis , arthritis , inflammation , disease , immunology , antibody , gastroenterology
The objective of this study was to assess the effect of vamorolone, a first-in-class dissociative steroidal compound, to inhibit inflammation when administered after disease onset in the murine collagen antibody-induced arthritis model of arthritis.