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Combination gas chromatography‐mass spectrometry
Author(s) -
Leemans F. A. J. M.,
McCloskey James A.
Publication year - 1967
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02908363
Subject(s) - mass spectrometry , chromatography , gas chromatography , chemistry , impurity , mass spectrum , thermal decomposition , decomposition , gas chromatography–mass spectrometry , principal component analysis , analytical chemistry (journal) , organic chemistry , computer science , artificial intelligence
The direct combination of gas‐liquid chromatography with mass spectrometry represents one of the most powerful techniques available for the analysis of complex mixtures of lipids. Principal advantages are the extremely small amounts of material required, the relative speed of analysis, and the wealth of molecular structural information available. The ability to record rapidly several mass spectra of one emerging chromatographic peak may also frequently be of use in detecting impurities, unresolved mixtures, or thermal decomposition of the sample. In the development of new gas chromatographic analytical procedures, the combination instrument may frequently prove highly useful for following chemical reactions in the preparation of new types of derivatives for GLC.

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