Open AccessPre-cancerous changes in the nasal mucosa of atrophic rhinitis: A preliminary report
Author(s) -
V Raveenthiran
Publication year - 2005
Publication title -
indian journal of otolaryngology and head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 2231-3796
pISSN - 0973-7707
DOI - 10.1007/bf02907622
Subject(s) - medicine , malignancy , metaplasia , squamous metaplasia , dysplasia , pathology , malignant transformation , precancerous condition , otorhinolaryngology , intestinal metaplasia , atrophic gastritis , cancer , mucous membrane of nose , carcinoma in situ , carcinoma , epithelium , surgery , gastritis , stomach
Metaplasia is a known predisposing factor to malignancy. As squamous metaplasia is a regular feature of atrophic rhinitis, its relationship with cancer is examined in this cross-sectional study. Random punch biopsies of nasal mucosa obtained from 14 patients (6 male and 8 female) suffering from primary atrophic rhinins were studied. Squamous metaplasia was noted in 64%. Epithelial dysplasia and in-situ malignant transformation were noted in one patient each. This preliminary report suggests that the association of atrophic rhimitis and pre-cancerous lesions appear to be more than coincidental and it deserves further studies.