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A new broad spectrum antibacterial soap I. General properties
Author(s) -
Jungermann Eric,
Taber David
Publication year - 1971
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02890754
Subject(s) - antibacterial activity , hexachlorophene , soap , broad spectrum , chemistry , microbiology and biotechnology , bacteria , organic chemistry , biology , combinatorial chemistry , world wide web , genetics , computer science
The first soap germicide system to show activity against gram‐negative organisms is described. Addition of a new germicidal agent, 2‐hydroxy‐2′,4,4′‐trichlorodiphenyl ether, combination of hexachlorophene and triclocarban which has been used in a soap known to be effective against gram‐positive organisms, has broadened its antibacterial spectrum without impairing its mildness, safety and other desirable bar soap characteristics. Properties of the new system, including in vitro and in vivo tests of its antibacterial activity, efficacy and safety, are discussed.