Premium
Synergistic antioxidant effect of nucleic acids and tocopherols
Author(s) -
Ikeda Nobuo,
Fukuzumi Kazuo
Publication year - 1977
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02802036
Subject(s) - nucleic acid , chemistry , antioxidant , tocopherol , dna , biochemistry , rna , dna oxidation , organic chemistry , vitamin e , oxidative damage , gene
and Summary Nucleic acids acted as synergists with tocopherols in inhibiting the oxidation of methyl linoleate. DNA and RNA enhanced the activity of tocopherols to different extents in the order α‐>γ‐>δ‐tocopherol. Nucleic acids decreased the rates of consumption of tocopherol in the presence of oxi‐dizing methyl linoleate. Nucleic acids also decreased the rate of oxidation of tocopherols by PbO 2 . The synergistic effect of nucleic acids seemed to be caused by hydrogen bond formation with tocopherols which protected toco‐pherols from direct air oxidation.