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Analysis of trichlorocarbanilide and triclosan in soaps by reverse phase high pressure liquid chromatography
Author(s) -
George E. D.,
Hillier E. J.,
Krishnan S.
Publication year - 1980
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02678824
Subject(s) - chromatography , high performance liquid chromatography , triclosan , elution , reproducibility , chemistry , ether , phase (matter) , absorption (acoustics) , reversed phase chromatography , materials science , organic chemistry , medicine , pathology , composite material
A method has been developed for the rapid and direct analysis of bacteriostats (3,4,4′‐trichlorocarbanilide and 2,4,4′‐trichIoro‐2′ ‐hydroxydiphenyl ether) in soaps with the aid of reverse phase high pressure liquid chromatography (HPLC) The bacteriostats were conveniently analyzed by UV absorption detection at 280 nm. A typical analysis of bacteriostats by this method requires 15 min for sample preparation and 15 min for the HPLC run. As the system needs no equilibration time (isocratic elution), it is immediately and reproducibility.