Premium
The quantitative determination of small amounts of nitrile in long chain fatty amides
Author(s) -
Buswell Katherine M.,
Link W. E.
Publication year - 1964
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02676254
Subject(s) - nitrile , chloroform , chemistry , amide , solvent , chromatography , silica gel , organic chemistry
Small amounts of nitrile in long chain fatty amides can be determined by separating the nitrile from the amide on a silica gel column using chloroform as the eluting solvent. The amide stays on the column. After the chloroform is removed by evaporation, the nitrile can be dissolved in a suitable solvent and determined quantitatively either by IR spectrophotometry or by TLC. Determination by IR is much faster than by TLC, but when the nitrile is present at the level of 0.1% or lower, TLC gives more satisfactory results.