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Lipase catalyzed formation of fatty amides
Author(s) -
Bistline Raymond G.,
Bilyk Alexander,
Feairheller Stephen H.
Publication year - 1991
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02662325
Subject(s) - candida rugosa , rhizomucor miehei , lipase , fatty acid , chemistry , catalysis , substrate (aquarium) , organic chemistry , triacylglycerol lipase , amine gas treating , enzyme , biology , ecology
Certain lipase preparations were found to facilitate the preparation of fatty amides at 20°C in hexane. Lipase preparations investigated were from the fungi Candida rugosa, Rhizomucor miehei and porcine pancreas. Reactants were various primary alkylamines and fatty acid methyl esters or triglycerides. Moderate yields of fatty amides were obtained using a R. miehei lipase preparation which is immobilized on a solid support as catalyst, although all three lipase preparations showed some catalytic activity under these conditions and, in addition, showed different kinds of selectivity for fatty acid and alkylamine chain lengths. No reaction was observed in similar experiments using one fatty acid as the substrate or one secondary amine.