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Study on Skin‐Irritating and Biological Properties of Monoalkyl Phosphate Anionic Surfactants
Author(s) -
Imokawa G.
Publication year - 1979
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02660246
Subject(s) - phosphate , chemistry , irritation , biochemistry , biology , immunology
Monoalkyl phosphate type of low irritating anionic surfactants were investigated with respect to their effect on various biological systems including proteins, enzymes, and lysosomes. Our results indicated that a remarkably weak membrane rupture effect at a concentration less than critical micellar concentration is important for low irritating feature. Mechanism by which irritation is caused by surfact‐ants is discussed.