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Study on skin roughness caused by surfactants: II. Correlation between protein denaturation and skin roughness
Author(s) -
Imokawa G.,
Sumura K.,
Katsumi M.
Publication year - 1975
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02640737
Subject(s) - pulmonary surfactant , denaturation (fissile materials) , surface finish , potency , chemistry , in vivo , surface roughness , bovine serum albumin , human skin , materials science , biophysics , chromatography , composite material , in vitro , biochemistry , biology , nuclear chemistry , genetics , microbiology and biotechnology
An attempt to determine protein denaturing potency of typical surfactants has been made by measuring specific rotation of bovine serum albumin. The potencies obtained were examined in relation to the intensities of skin roughness in vivo caused by the surfactants, and a noticeable correlation was found between them. This fact also suggested that the cause of skin roughness may be attributed to a certain extent to adsorption of surfactants. In addition, this technique is very useful in predicting the skin roughening potency of a surfactant without using human skin.