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Autoxidation products from cholesterol
Author(s) -
Fioriti J. A.,
Sims R. J.
Publication year - 1967
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02639261
Subject(s) - autoxidation , sterol , chemistry , decomposition , epoxide , thin layer chromatography , cholesterol , ultraviolet light , ultraviolet , melting point , gas chromatography , chromatography , organic chemistry , photochemistry , catalysis , materials science , biochemistry , optoelectronics
Thin‐layer chromatography and gas‐liquid chromatography were used to separate and identify products from the autoxidation of cholesterol. Both cholesterol‐ a ‐epoxide and 1,4‐cholestadien‐3‐one were found. In addition, several other compounds, identified also by previous workers, were shown to be present. Autoxidation in bulk was quite slow at 82C, requiring several weeks for development of detectable quantities of decomposition products. The reaction could be accelerated by irradiation with ultraviolet light or by heating the sterol above its melting point.