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The examination of fats and fatty acids for toxic substances
Author(s) -
Firestone David,
Horwitz William,
Friedman Leo,
Shue Glen M.
Publication year - 1961
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02637977
Subject(s) - chemistry , oleic acid , fatty acid , food science , organic chemistry , weanling , stearic acid , triolein , raw material , chromatography , biochemistry , biology , lipase , enzyme , endocrinology
The chick edema disease factor was found to be present in a number of distillates and residues that were obtained during the production of commercial fatty acids. The raw materials from which the toxic samples were produced included inedible animal tallows, acidulated vegetable oil foots, and oils recovered from tin plate manufacture. The chick edema factor was found to be present in several oleic acids and in a triolein. Twenty stearic acid samples which were examined were nontoxic. The nonurea adduct‐forming fatty acids that were isolated from commercial oleic acids and various distillates and residues from the manufacture of commercial fatty acids were found to be toxic to weanling rats even after hydrogenation. Analysis of the nonurea‐adducting monomers that were isolated from a fatty acid by‐product distillate indicated the presence of cyclic structures.