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Derivatization of keto fatty acids: I. Synthesis and mass spectrometry of thiazolidinones
Author(s) -
Ahmad Nasirullah F.,
Osman S. M.,
Pimlott W.
Publication year - 1982
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02634424
Subject(s) - derivatization , chemistry , fragmentation (computing) , alkyl , mass spectrometry , gas chromatography–mass spectrometry , mass spectrum , organic chemistry , chromatography , medicinal chemistry , computer science , operating system
The synthesis of alkyl chain‐substituted thiazolidinones from oxo acids is described. Reactions of mercaptoacetic acid with three oxoesters, methyl 10‐oxoundecanoate, methyl 12‐oxooctadecanoate and methyl 9,10‐dioxooctadecanoate gives excellent yields of the corresponding thazolidinones. Mass spectral fragmentation patterns of these long‐chain thiazolidinone derivatives are discussed.