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Determination of 1‐alkene‐1,3‐sultones in alkylethoxy sulfates
Author(s) -
Connor D. S.,
Kowollik H.,
Thomas D. W.
Publication year - 1976
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02633300
Subject(s) - dehydrohalogenation , alkene , isotope dilution , chemistry , chromatography , gas chromatography , thin layer chromatography , mass spectrometry , dilution , organic chemistry , catalysis , physics , thermodynamics
1‐Alkene‐1,3‐sultones, which have been found as skin sensitizers in certain batches of alkylethoxy sulfates, are measured by an isotope dilution method, using a 13 C‐labeled sultone. The sultone is recovered by thin layer chromatography and gas chromatography, and its dilution with unlabeled sultone is measured by mass spectrometry. Chlorosultones, also implicated as sensitizers, are determined at the same time by a dehydrohalogenation treatment that converts them to unsaturated sultones.