Premium
The synthesis of tritium labeled 9, 10‐oleic acid
Author(s) -
Tenny K. S.,
Gupta S. C.,
Nystrom R. F.,
Kummerow F. A.
Publication year - 1963
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02632574
Subject(s) - tritium , oleic acid , elaidic acid , stearic acid , chemistry , catalysis , tritium illumination , nuclear chemistry , palladium , radiochemistry , specific activity , activated charcoal , organic chemistry , adsorption , linoleic acid , biochemistry , fatty acid , enzyme , physics , nuclear physics
Tritium labeled 9,10‐oleic acid was prepared from stearolic acid by reduction with tritium gas, in the presence of 5% Palladium on Charcoal catalyst, at room temperature and under partial vacuum. No stearic or elaidic acids were formed. Unreacted stearolic acid was removed by low temperature erystallization from Skellysolve F. The tritium labeled cis 9,10‐oleic acid was prepared with a specificity of greater than 90% of the activity at the 9 and 10 positions. Specific radio‐activity of the oleic acid was 1000 me of Tritium/g. Tritium labeled stearic acid with a specific activity of 927 me of Tritium/g was also prepared.