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Free radical addition of thiolacetic acid to esters and amides of unsaturated acids and screening of the products for antimicrobial activity
Author(s) -
Mod R. R.,
Harris J. A.,
Arthur J. C.,
Magne F. C.,
Sumrell G.,
Novak A. F.
Publication year - 1976
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02586279
Subject(s) - antimicrobial , chemistry , candida albicans , escherichia coli , staphylococcus aureus , aspergillus niger , organic chemistry , biochemistry , bacteria , microbiology and biotechnology , biology , genetics , gene
Free radical addition of thiolacetic acid to terminal and internal double bonds of mono‐and diunsaturated amides, as well as to unsaturated esters, was achieved by irradiation with Cobalt‐60. Screening for antimicrobial activity against Staphylococcus aureus, Escherichia coli, Aspergillus species, Torula species, and Candida albicans indicated that terminal addition products may be more active than internal addition products.