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Recovery of fish oil‐derived fatty acids in lymph of thoracic duct‐cannulated wistar rats
Author(s) -
Reicks Marla,
Hoadley James,
Satchithanandam Subramaniam,
Morehouse Kim M.
Publication year - 1990
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02562420
Subject(s) - docosahexaenoic acid , eicosapentaenoic acid , fish oil , menhaden , chemistry , lymph , fatty acid , food science , biochemistry , polyunsaturated fatty acid , medicine , biology , fishery , pathology , fish <actinopterygii>
The absorption of equivalent doses of eicosapentaenoic and docosahexaenoic acids was compared in rats when administered as the ethyl ester concentrate, ethyl ester concentrate plus olive oil, free fatty acid or triacylglycerol (menhaden oil). Lymph was collected from a thoracic duct cannula for 24 hr after dosing via an indwelling duodenal catheter. After 24 hr, the absorption of eicosapentaenoic acid was greater for the free fatty acid and menhaden oil than for the ethyl ester form, but docosahexaenoic acid absorption was comparable for all forms. Other rats had greater plasma levels of eicosapentaenoic and docosahexaenoic acids 5 hr after oral gavage dosing with menhaden oil than did rats dosed with the ethyl ester form.