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Hormonal regulation of phosphatidylcholine metabolism and transport
Author(s) -
Coletti D.,
Palleschi S.,
Adamo S.,
Silvestroni L.
Publication year - 1999
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02562233
Subject(s) - embryology , medicine , library science , anatomy , computer science
Phosphatidylcholine (PC), a major membrane phospholipid, is\udinvolved in a wide variety of celi functions. Invol vement of PC\udin signal transduction [i.e., phospholipase D (PLD)-mediated\udPC hydrolysis] is a well-characterized process, but very little\udis known about its metabolism after hormonal stimulus. We\udinvestigated this process in a weH-characterized experimental\udsystem, consisting ofL6 myogenic cells stimulated by Arg8_\udvasopressin (AVP), which rapidly activates PLD, inducing\udmeasurable PC hydrolysis in the plasma membrane (PM)