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Synthesis and properties of N α ‐lauroyl‐L‐arginine dipeptides from collagen‐lauroyl‐L‐arginine dipeptides from collagen
Author(s) -
Molinero J.,
Julia M. R.,
Erra P.,
Robert M.,
Infante M. R.
Publication year - 1988
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02544523
Subject(s) - arginine , pulmonary surfactant , chemistry , hydrolysate , peptide , amino acid , dipeptide , preservative , biochemistry , organic chemistry , hydrolysis
In order to obtain protein‐based amphoteric surfactants with antimicrobial properties, N α ‐lauroyl arginine dipeptides have been prepared by condensation between N α ‐lauroyl arginine and amino acids which come from a collagen hydrolysate. Some surfactant properties and the minimum inhibitory concentration against Gram positive and Gram negative bacteria have been evaluated. All types of compounds presented a surfactant‐like behavior. Furthermore, the compounds described in this paper may be considered as mild preservative or protective substances.