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Derivatization of keto fatty acids. III. synthesis of terminal thiazole and oxazole derivatives from α‐bromoketones
Author(s) -
Rafat Husain S.,
Ahmad F.,
Ahmad M.,
Osman S. M.
Publication year - 1984
Publication title -
journal of the american oil chemists' society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 117
eISSN - 1558-9331
pISSN - 0003-021X
DOI - 10.1007/bf02542175
Subject(s) - oxazole , thiazole , chemistry , thiourea , derivatization , acetamide , alkyl , urea , organic chemistry , combinatorial chemistry , high performance liquid chromatography
The synthesis of alkyl chain substituted thiazole and oxazole derivatives is described. The reaction of 11‐bromo‐10‐oxoundecanoic acid with thiourea and acetamide yielded terminally located thiazole and oxazole derivatives, respectively. A similar treatment with urea produced the unexpected urea‐substituted product, together with an unidentified product.