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Boreal freshwater fish diet modifies the plasma lipids and prostanoids and membrane fatty acids in man
Author(s) -
Ågren J. J.,
Hänninen O.,
Laitinen M.,
Seppänen K.,
Bernhardt I.,
Fogelholm L.,
Herranen J.,
Penttila I.
Publication year - 1988
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02536338
Subject(s) - docosahexaenoic acid , eicosapentaenoic acid , polyunsaturated fatty acid , pike , herring , rainbow trout , fish meal , biology , phospholipid , triglyceride , fatty acid , food science , chemistry , endocrinology , medicine , cholesterol , biochemistry , fish <actinopterygii> , fishery , membrane
The effect of fish diet on 43 healthy male students was studied. They ate a fish‐containing meal for 15 weeks on an average of 3.7 times per week. Twenty‐one of them voluntarily restricted their lipid intake while the rest ate normally. Controls continued their usual eating habits (19 students). The meals consisted of Finnish freshwater fish (87%) (vendace, pike, perch and rainbow trout) and brackish water fish (13%) (Baltic herring) that provided about 1 g of ω‐3 polyunsaturated fatty acids per day (0.25 g eicosapentaenoic acid and 0.55 g docosahexaenoic acid). During the diet, ω‐3 fatty acids increased in erythrocyte ghosts and platelets at the expense of ω‐6 fatty acids. The concentration of serum cholesterol diminished in those fish consumers who lowered their lipid intake. Apolipo‐protein A 1 and B were lowered in both fish‐consuming groups. Triglyceride levels also showed a tendency to decrease. The formation of thromboxane B 2 during incubation of whole blood decreased in both fish‐consuming groups. The decrease of plasma 6‐keto‐PGF 1α was not statistically significant, if compared with the controls. The results obtained indicate that a moderate intake of fish‐containing meals has some beneficial effects on the plasma lipid and prostanoid metabolism, when coronary heart disease risk factors are considered.