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Accumulation of eicosapentaenoic acid in plasma phospholipids of subjects fed canola oil
Author(s) -
Corner Elizabeth J.,
Bruce Vivian M.,
McDonald Bruce E.
Publication year - 1990
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02536008
Subject(s) - canola , phospholipid , sunflower oil , food science , linoleic acid , chemistry , fatty acid , eicosapentaenoic acid , ethanolamine , linolenic acid , phosphatidylcholine , lipidology , zoology , polyunsaturated fatty acid , biochemistry , biology , membrane
The metabolism of α‐linolenic acid from canola oil was studied in eight normolipidemic men. The 42‐day study was divided into three periods: a 6‐day pre‐experimental and two 18‐day experimental. Approximately 75% of the dietary fat (28% of total energy) was provided by a mixture of fats during the pre‐experimental period and either canola oil (CO) or sunflower oil (SO) during the experimental periods. The CO and SO diets were fed in a cross‐over design. The ratios of linoleic to linolenic acid were 2.6∶1 and 73.9∶1 in the CO and SO diets, respectively. Dietary fat source had an effect on plasma phospholipid fatty acids: 18∶1n−9, 18∶3n−3 and 20∶5n−3 were higher (p<0.05), and 18∶2n−6 was lower in the phosphatidylcholine fraction; 18∶1n−9 was higher and 20∶4n−6 lower in the phosphatidyl‐ethanolamine fraction; and 18∶1n−9 and 20∶5n−3 were higher and 20∶4n−6 and 22∶6n−3 were lower in the alkenylacyl‐ethanolamine phospholipid fraction on the CO diet as compared to the SO diet. Consumption of the canola oil diet resulted in higher n−3 fatty acid levels and lower n−6 fatty acid levels in plasma phospholipids than consumption of the sunflower oil diet.