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Lactation curves and effect of pup removal on milk fat of C57BI/6J mice fed different diet fats
Author(s) -
Teter Beverly B.,
Sampugna Joseph,
Keeney Mark
Publication year - 1992
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02535872
Subject(s) - lactation , clinical chemistry , low fat diet , milk fat , lipidology , biology , fatty acid , period (music) , medicine , endocrinology , zoology , chemistry , food science , pregnancy , biochemistry , obesity , linseed oil , genetics , physics , acoustics
Groups of C57BI/6J mice, fed either a cis (C‐Diet) or trans diet (T‐Diet) were milked without preconditioning at 6, 8, 10 and 12 days postpartum . On day 10, groups of mice were also milked 4, 6 and 18 h after separation of the pups. Except for the 18‐h separation, all T‐Diet fed animals produced milk of lower fat content than did the C‐Diet animals ( P <0.001) throughout the lactation period measured. In the C‐Diet mice, the 6‐h separation period resulted in a decrease ( P <0.03) in fat, but the diet‐depressed milk fat of T‐Diet animals was not decreased further until the 18‐h separation period. Milk volume increased as lactation progressed and was greatly increased as a result, of preconditioning ( P <‐0.001), even at 4 h of separation when fat was not reduced, and was always greater for T‐Diet animals. Within diet groups, fatty acid composition was similar throughout the lactation period studied and was not affected by preconditioning, except in the 18‐h separation period, when de novo fatty acids were significantly reduced ( P ≤0.05). The data are consistent with the hypothesis that preconditioning results in lowered milk fat values and that preconditioning techniques can explain discrepancies in literature values for murine milk fat.