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Chaulmoogric acid: Assimilation into the complex lipids of mycobacteria
Author(s) -
Cabot Myles C.,
Goucher Charles R.
Publication year - 1981
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02535690
Subject(s) - assimilation (phonology) , lipidology , fatty acid , biochemistry , clinical chemistry , mycobacterium , chemistry , antimicrobial , organism , microbiology and biotechnology , membrane , bacteria , biology , paleontology , philosophy , linguistics , genetics
Abstract Lipid analysis of Mycobacterium vaccae , grown in the presence of chaulmoogric acid, demonstrates that this cyclopentenyl fatty acid is taken up by the organism and incorporated into cellular phospholipids and triacylglycerols. As cell growth is retarded by the addition of chaulmoorgric acid to the growth medium, it is possible that the antimicrobial properties of this compound result from a perturbation of membrane processes.