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Human placenta gangliosides
Author(s) -
Taki Takao,
Matsuo Kenichi,
Yamamoto Kaname,
Matsubara Toshiko,
Hayashi Akira,
Abe Tadayuki,
Matsumoto Makoto
Publication year - 1988
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02535457
Subject(s) - exoglycosidase , chromatography , placenta , ganglioside , chemistry , proton magnetic resonance , mass spectrometry , column chromatography , silica gel , biochemistry , glycan , biology , glycoprotein , nuclear magnetic resonance , fetus , pregnancy , physics , genetics
Gangliosides extracted from human placenta were composed of four major components (G1–G4), which were purified by silica beads column chromatography. The structures of these gangliosides were analyzed by exoglycosidase treatments, 400 MHz proton magnetic resonance spectroscopy and gas chromatography‐mass spectrometry and were concluded to be as follows:Gangliosides containing more than 10 sugar residues were observed in addition to the above four major components. But ganglio‐series gngliosides were undetectable in the placenta.