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Utilization and metabolism of dietary sterols in the honey bee and the yellow fever mosquito
Author(s) -
Svoboda James A.,
Thompson Malcolm J.,
Herbert Elton W.,
Shortino Thomas J.,
SzczepanikVanleeuwen Patricia A.
Publication year - 1982
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02535107
Subject(s) - lipidology , clinical chemistry , honey bee , biology , metabolism , food science , botany , biochemistry
The honey bee, Apis mellifera , does not convert C 28 and C 29 phytosterols to cholesterol as found in most previous studies of phytophagous or omnivorous insects, but instead the workers and queens selectively transfer 24‐methylenecholesterol, sitosterol and isofucosterol from their endogenous sterol pools to the brood larvae regardless of the sterol in the worker diet. Administering radiolabeled sterols by feeding and injection has made it possible to trace this selective transfer through a second generation of the honey bee. In further comparative sterol metabolism studies, the yellow fever mosquito, Aedes aegypti , was shown to be capable of dealkylating and converting a radiolabeled C 29 dietary sterol ([ 14 C] sitosterol) to cholesterol. Metabolic studies with several radiolabeled dietary sterols and an inhibitor of steroid metabolism in the yellow fever mosquito further verified this capability.