Premium
Absorption and distribution of orally administered jojoba wax in mice
Author(s) -
Yaron A.,
Samoiloff V.,
Benzioni A.
Publication year - 1982
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02535098
Subject(s) - wax , lipidology , absorption (acoustics) , distribution (mathematics) , clinical chemistry , epicuticular wax , chemistry , wax ester , shrub , botany , biology , chromatography , biochemistry , mathematical analysis , physics , mathematics , acoustics
Abstract The liquid wax obtained from the seeds of the arid‐land shrub jojoba ( Simmondsia chinensis ) is finding increasing use in skin treatment preparations. The fate of this wax upon reaching the digestive tract was studied. 14 C‐Labeled wax was administered intragastrically to mice, and the distribution of the label in the body was determined as a function of time. Most of the wax was excreted, but a small amount was absorbed, as was indicated by the distribution of label in the internal organs and the epididymal fat. The label was incorporated into the body lipids and was found to diminish with time. Lipids 17: 169–171. 1982.