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Preparation of cis,cis,cis ‐5,8,11‐eicosatrienoic acid from arachidonic acid
Author(s) -
Ghosh Amitabha,
Koley Malati,
Dutta J.
Publication year - 1982
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534947
Subject(s) - lipidology , chemistry , arachidonic acid , clinical chemistry , chromatography , biochemistry , enzyme
Arachidonic acid was reduced by hydrazine to yield isomeric eicosatrienoic acids with other products. Methyl cis,cis,cis ‐5,8,11‐eicosatrienoate was isolated from the products by silver ion chromatography and preparative gas liquid chromatography in 8% yield. The structure was confirmed by spectral studies and oxidative degradation.