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Mass spectrometric evidence for the presence of platelet‐activating factor (1‐0‐alkyl‐2‐acetyl‐ sn ‐glycero‐3‐phosphocholine) in human amniotic fluid during labor
Author(s) -
Nishihira Jun,
Ishibashi Teruo,
Imai Yoh,
Muramatsu Toshio
Publication year - 1984
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534724
Subject(s) - amniotic fluid , chemistry , alkyl , platelet activating factor , phospholipid , ether , chromatography , phosphocholine , residue (chemistry) , clinical chemistry , biochemistry , organic chemistry , endocrinology , pregnancy , biology , fetus , genetics , membrane , phosphatidylcholine
Evidence is presented for the existence of platelet‐activating factor (PAF) in human amniotic fluid during labor by gas‐liquid chromatographic (GLC) and mass‐spectrometric (MS) analysis. The unique ether‐linked phospholipid was identified only in an amniotic fluid obtained from women during labor, and its alkyl side chain was composed exclusively of octadecyl residue.