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Effect of age on plasma bile acids and lipid components in the rat
Author(s) -
Suzuki Hiramitsu,
Hayakawa Seiichi,
Tajima Makoto
Publication year - 1983
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534678
Subject(s) - chenodeoxycholic acid , deoxycholic acid , clinical chemistry , cholic acid , lipidology , bile acid , chemistry , cholesterol , lithocholic acid , medicine , chromatography , biochemistry , endocrinology , biology
With increasing age, total plasma bile acid contents increased in rats over a period of 11 months, and also total plasma cholesterol and carcass fat contents increased in the same manner. Plasma showing high bile acid levels at 11 months was found by means of high performance liquid chromatography to contain cholic acid as one of the major components, chenodeoxycholic acid and trace deoxycholic acid. These results suggest that there are close relationships between the plasma bile acids and age‐dependent changes of lipid components in the rat.