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A nuclear magnetic resonance spectroscopic investigation of the headgroup motions of lysophospholipids in bilayers
Author(s) -
Wu W.,
Stephenson' F. A.,
Mason J. T.,
Huang C.
Publication year - 1984
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534612
Subject(s) - chemistry , nuclear magnetic resonance spectroscopy , nuclear magnetic resonance , bilayer , phospholipid , resonance (particle physics) , membrane , crystallography , stereochemistry , physics , biochemistry , atomic physics
Fully hydrated lysophospholipids in both the gel and the liquid crystalline states have been shown to exhibit negative phosphorus chemical shift anisotropies (Δσ) by 31 P nuclear magnetic resonance (NMR). The magnitude of Δσ for monoacyl lysophospholipids is found to be smaller than that of the corresponding diacyl phosphospholipids in bilayers by about a factor of two. We present evidence to suggest that the reduction in Δσ can be attributed primarily to an additional motional averaging of the lysophospholipid headgroup, and the additional motion can best be explained by rapid rotational motions of the headgroup about the C(1)‐C(2) glycerol bond.