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A simple synthesis of 5,8,11‐eicosatrienoic acid
Author(s) -
Parish Harlie A.,
Gilliom Richard D.,
Purcell William P.
Publication year - 1983
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534568
Subject(s) - chemistry , quinoline , recrystallization (geology) , solvent , catalysis , chromatography , organic chemistry , paleontology , biology
A straighforward synthesis of Z,Z,Z‐5,8,11‐eicosatrienoic acid is described that gives a pure product without chromatography. The C 20 ‐polyacetylenic acid is purified by recrystallization and then reduced by a Lindlar catalyst in an aprotic solvent with a trace quantity of quinoline.