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Dihomo‐γ‐linolenic acid reverses hypertension induced in rats by diets rich in saturated fat
Author(s) -
Hassall Cedric H.,
Kirtland Stephen J.
Publication year - 1984
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534530
Subject(s) - clinical chemistry , lipidology , gamma linolenic acid , palmitic acid , chemistry , linolenic acid , saturated fat , food science , saturated fatty acid , polyunsaturated fatty acid , coconut oil , fatty acid , medicine , endocrinology , biochemistry , linoleic acid , cholesterol
This study has shown that hypertension induced in rats by a diet rich in saturated fat (16% coconut oil, 4% palmitic acid by weight) is reversed by the addition of the essential fatty acid, dihomo‐γ‐linolenic acid (DHLA), at 5.0% but not at 0.5% of dietary energy. This potent effect of DHLA has been attributed to modulation of prostaglandin biosynthesis.